Sitagliptin is used to treat high blood sugar levels caused by type 2 diabetes. It's used along with lifestyle changes such as improved diet and exercise, and avoiding smoking.
Sitagliptin belongs to a class of drugs called dipeptidy! peptidase-4 (DPP-4) inhibitors. Insulin is a chemical in your body that helps remove sugar from your blood and moves it to cells, where it can be used for energy. Hormones in your body called incretins regulate the production and release of insulin. Sitagliptin works by protecting incretin hormones so they aren't broken down too quickly. This helps your body use insulin better and lowers your blood sugar.